Strella Biotechnology Continues Scaling Up

Katherine Sizov (right) and Malika Shukurova (left) earned the 2019 President’s Innovation Prize for their startup, Strella Biotechnology.

“Fruit hacking” startup Strella Biotechnology, founded by students and faculty advisors from the School of Engineering and Applied Science (SEAS) and the School of Arts and Sciences (SAS), tackles food waste by monitoring fruit ripeness. No stranger to media coverage, Strella and co-founder Katherine Sizov have previously been spotlighted for receiving the 2019 President’s Innovation Prize, which included $100,000 of financial support, a $50,000 living stipend for both awardees, and a year of dedicated co-working and lab space at the Pennovation Center. 

Recently, Michael Birnbaum of the Washington Post spoke with Sizov about the hard work and flexibility it took to propel the company’s successful scaling endeavors: Strella is now monitoring 15 percent of all U.S. apples.  

“Sizov, 24, wants to eliminate food waste one fruit at a time. In central Washington, it was an effort that required almost as much quick footwork as the épée squad she captained as a championship fencer in college. One moment, she was trying to beam the sensor’s WiFi signal through the reception black hole of millions of apples, which cause transmission issues because of their high water content. The next, she was sitting down with laconic apple growers with orchards planted generations ago, trying to convince them she could help them avoid wasted fruit. By day’s end, she might be folding her 6-foot frame into the passenger seat of a rental car, balancing her laptop on her knees and trying to win over Silicon Valley investors on Zoom calls using skills she had picked up partly by watching YouTube tutorials.”

Read Michael Birnbaum’s Fighting food waste, one apple at a time” for more about Sizov’s motivation, background and process.

Strella Biotechnology was founded by Penn alumna Katherine Sizov (Bio 2019) and was initially developed in the George H. Stephenson Foundation Educational Laboratory, the biomakerspace and primary teaching lab of the Department of Bioengineering. Sizov and Penn Bioengineering alumna Malika Shukurova (BSE 2019) won a President’s Innovation Prize in 2019. Read more BE blog stories featuring Strella Biotechnology.

Penn Bioengineering Alumna Cynthia Reinhart-King is President Elect of BMES

Dr. Cynthia Reinhart-King, Engineering, BME, Photo by Joe Howell

Penn Bioengineering alumna Cynthia Reinhart-King, Cornelius Vanderbilt Professor of Engineering and Professor of Biomedical Engineering at Vanderbilt University, was elected the next President of the Biomedical Engineering Society (BMES), the largest professional society for biomedical engineers. Her term as president-elect started at the annual BMES meeting in October 2021.

Reinhart-King graduated with her Ph.D. from Penn Bioengineering in 2006. She studied in the lab of Daniel Hammer, Alfred G. and Meta A. Ennis Professor in Bioengineering and Chemical and Biomolecular Engineering as a Whitaker Fellow and went on to complete postdoctoral training as an Individual NIH NRSA postdoctoral fellow at the University of Rochester. Prior to joining Vanderbilt, she was on the faculty of Cornell University and received tenure in the Department of Biomedical Engineering. The Reinhart-King lab at Vanderbilt “uses tissue engineering, microfabrication, novel biomaterials, model organisms, and tools from cell and molecular biology to study the effects of mechanical and chemical changes in tissues during disease progression.”

Reinhart-King gave the 2019 Grace Hopper Distinguished Lecture, sponsored by the Department of Bioengineering. This lecture series recognizes successful women in engineering and seeks to inspire students to achieve at the highest level. She is a recipient of numerous prestigious awards, including the Rita Schaffer Young Investigator Award in 2010, an NSF CAREER Award, and the Mid-Career Award in 2018 from BMES.

In a Q&A on the BMES Blog, Reinhart-King said that:

“BMES is facing many challenges, like many societies, as we deal with the hurdles associated with COVID-19 and inequities across society. We must continue to address those challenges. However, we are also in a terrific window of having robust membership, many members who are eager to get involved with the society’s activities, and a national lens on science and scientists. One of my goals will be to identify and create opportunities for our members to help build the reach of the society and its member.”

Read “Cynthia Reinhart-King is president-elect of the Biomedical Engineering Society” in Vanderbilt News.

Alumnus Jackson Foster on ’20 in Their 20s’ List

Jackson Foster

Penn Bioengineering alumnus Jackson Foster (BSE 2014) was included in the Los Angeles Business Journal’s 2021 “20 in Their 20s” list, recognizing rising entrepreneurial stars of L.A.’s business community. Foster is the Founder and Chief Executive of the San Francisco-based Edily Learning, an education technology company which has created an app focused on education, learning goals, and personalized content using a TikTok-like algorithm.

After completing his bachelor’s degree, Foster earned his M.B.A in Business Administration and Management at the UCLA Anderson School of Management.

Read “20 in Their 20s: Jackson Foster” in the Los Angeles Business Journal.

Alumni Spotlight: Jane Shmushkis

Jane graduated in Fall 2017 with both a B.S.E. in Bioengineering (with a Medical Devices Concentration) and M.S.E. in Bioengineering. Jane is currently an Automation Engineer at Mosa Meat (Maastricht, Netherlands) working on laboratory tools to scale up cultured beef production. Formerly, she was a Research & Development Engineer at Opentrons (Brooklyn, New York) working on affordable robots for life sciences research. She is also an instructor with Genspace Community Biology Lab (Brooklyn, New York).

Jane Shmushkis (BSE/MSE 2017)

“While at Penn, I worked in the Stephenson Foundation Educational Laboratory and Bio-MakerSpace and in the Chow Lab as a student researcher. The educational lab was a free space to mess around with rapid prototyping tools, including 3D printing, laser cutting, Arduino, and much more. The experience in synthetic biology research encouraged me to think of biology with an engineering lens and to have the confidence to plan my own experiments. The people I got to work with at the BioMakerSpace and the Chow Lab kept me optimistic through challenging semesters and excited to learn.

With this excitement to keep learning, I decided to submatriculate into the Bioengineering Master’s program. Because of the program’s flexibility, I could choose from a mix of project-based courses, like Biomechatronics and Modeling Biological Systems, and literature-based courses, like Tissue Engineering and Musculoskeletal Bioengineering. Outside of Bioengineering, I took classes to sharpen skills in part fabrication (Machine Design and Manufacturing) and programming (Computer Vision & Computational Photography). This breadth helped me realize how much I could do with a foundation in coding and mechanical design and an understanding of the life sciences.

Beyond Penn Engineering, I was involved in Penn Dance Company, CityStep Penn, and the Science & Technology Wing. Penn Dance was a necessary break for my body and mind. CityStep was a way to connect with the larger Philadelphia community through performing arts. STWing showed me how playful engineering can be. After a couple years on campus, I also built up the confidence to bike off campus. If you have a good helmet and quick reflexes, I really recommend it to explore more of Philly!”

This post is part of BE’s Alumni Spotlight series. Read more testimonies from BE Alumni on the BE website.

Bioengineering Graduate Sofia Gonzalez Honored with Leadership Awards

Sofia Gonzalez (BSE & MSE 2021)

Sofia Gonzalez, who graduated with both bachelor’s and master’s degrees in Bioengineering this spring, was one of a select number of Penn students to receive 2021 Student Leadership Awards. Gonzalez was awarded a Penn Alumni Student Award of Merit as well as the William A. Levi Kite & Key Society Award for Service and Scholarship. Awardees were celebrated during the university’s annual Ivy Day, “a tradition recognizing students’ leadership, service, and scholarship for nearly 150 years.”

Gonzalez discussed the importance of diverse representation in the Student Leadership Awards Book:

“Sofia reflected that on countless college tours, she noticed a striking pattern: only one of the ambassadors she encountered was a female engineer, and none of them were Latinx. While the nation was reckoning with racism, Sofia was leading critical discussions about how Kite & Key could improve in areas of diversity, equity, and inclusion to mirror the Penn student body. Sofia is now graduating, confident that she took measurable strides toward breaking the cycle of underrepresentation at America’s first University. Sofia’s work leaves a lasting legacy at Penn and beyond.”

Gonzalez also served as a Senior Advisor to the Biomedical Engineering Society (BMES) and as President of the Kite and Key Society, a society which welcomes all visitors to campus, acquaints prospective students and families with the undergraduate experience, and fosters a community of students dedicated to serving the University of Pennsylvania. Having completed her degrees, Gonzalez is headed for the first year of a rotational program as a member of the Merck Manufacturing Leadership Development Program in Durham, NC.

Following her time at Merck, Gonzalez will continue her education at the MIT Sloan School of Management. Gaining admission to the M.B.A. program via the Early Admission offering, she will matriculate within the following five years.

Read the full list of 2021 award winners and learn more about the awards on the Ivy Day website.

Strella Biotechnology Featured in Philly Mag

NextUp, a regular feature of Philadelphia Magazine that “highlights the local leaders, organizations and research shaping the Greater Philadelphia region’s life sciences ecosystem,” ran a profile of Philly-based agricultural startup Strella Biotechnology. Founded by Penn alumna Katherine Sizov (Bio 2019) and winner of a 2019 President’s Innovation Prize, Strella Biotech seeks to reduce food waste through innovative biosensors, and was initially developed in the George H. Stephenson Foundation Educational Laboratory, the biomakerspace and primary teaching lab of the Department of Bioengineering.

Sizov says the coronavirus pandemic has made the volatility of grocery stores’ offerings even more apparent. Last April, the Produce Marketing Association estimated that nearly $5 billion of fresh fruits and vegetables had gone to waste in the first month of the pandemic due to the complex supply chain’s inability to quickly redirect shipping and distribution. ‘In a way, I think COVID-19 has helped us realize how delicate and fragile supply chains are,’ she says. ‘We are working to create better, stronger supply chains that are economically and environmentally sustainable for everyone involved — researchers, growers, packagers, distributors, retailers, and consumers.'”

Read “NextUp: The Philly Startup Using Biosensors to Combat Food Waste and Improve Supply Chains” in Philly Mag.

Read more BE blog stories featuring Strella Biotechnology.

Katherine Reuther Appointed Practice Associate Professor in Bioengineering

Katie Reuther, PhD, MBA

Katherine (Katie) Reuther, Ph.D., M.B.A. will return to Penn Engineering in July 2021 as the new Executive Director of Penn Health-Tech (PHT) and as Practice Associate Professor in Bioengineering. Reuther is an alumna of Penn Bioengineering, having obtained her Ph.D. at Penn in the laboratory of Louis Soslowsky, Fairhill Professor in Bioengineering and Orthopaedic Surgery.

“Dr. Reuther is a role model for biomedical innovation, linking formal training in engineering and entrepreneurship with deep practical experience in leading technologies through the commercialization pipeline. Dr. Reuther graduated with her Bachelor of Science in Biomedical Engineering, Magna cum Laude, from the College of New Jersey; she obtained her Ph.D. in Bioengineering at Penn in the laboratory of Dr. Louis Soslowsky and completed her MBA at Columbia, where she currently is a Senior Lecturer in Design, Innovation, and Entrepreneurship in the Department of Biomedical Engineering. During her tenure at Columbia, Dr. Reuther helped create and led Columbia’s Biomedical Engineering Technology Accelerator (BiomedX), overseeing more than 60 technologies leading to $80M in follow-on funding and 18 licenses to start-ups or start-ups industry.  Introducing both new courses and a new curriculum in biomedical innovation, Dr. Reuther was recently awarded Columbia’s highest teaching honor, the ‘2021 Presidential Award for Outstanding Teaching,’ this Spring as a recognition of her excellence in teaching and dedication to students.

Katie has extensive experience in developing and translating early-stage medical technologies and discoveries and providing formal educational training for aspiring medical entrepreneurs.  Dr. Reuther served as Director of Masters’ Studies for the Department of Biomedical Engineering and spearheaded the development of a graduate-level medical innovation program, including an interdisciplinary course available to scientists, engineers, and clinicians. Dr. Reuther provided advising and educational support to more than 100 student/faculty teams and start-ups, as they worked to develop and commercialize medical technologies. She will bring these extensive skills to PHT and Penn Bioengineering in two new, hands-on graduate courses in medical innovation centered around Penn Health-Tech ventures.”

Read the full announcement in OVPR news.

Claudia Loebel Appointed Assistant Professor at the University of Michigan

by Mahelet Asrat

Claudia Loebel, MD, PhD (Photo/Mel Evans)

The Department of Bioengineering is proud to congratulate Claudia Loebel, M.D., Ph.D. on her appointment as Assistant Professor in the Department of Materials Science and Engineering at the University of Michigan. Loebel is part of the University of Michigan’s Biological Sciences Scholar program, which recruits junior instructional faculty in major areas of biomedical investigation. Loebel’s appointment will begin in Fall 2021.

Loebel got her M.D. in 2011 from Martin-Luther University in Halle-Wittenberg, Germany and her Ph.D. in Health Sciences and Technology from ETH Zurich, Switzerland in 2016. There she worked under her advisors Professors Marcy Zenobi-Wong from ETH Zurich and David Eglin from AO Research Institute Davos. At Penn, she conducted postdoctoral research in the Polymeric Biomaterials Laboratory of Jason Burdick, Robert D. Bent Professor in Bioengineering, and as a Visiting Research Scholar in the Mauck Laboratory of the McKay Orthopaedic Research Laboratory in the Perelman School of Medicine.

Loebel was awarded a K99/R00 Pathway to Independence Award through the National Institutes of Health (NIH), which supports her remaining time as a postdoc as well as her time as an independent investigator at the University of Michigan. Loebel is excited about training the next generation of scientists and engineers and being part of their journey in becoming independent and diverse thinkers.

Loebel’s research area is inspired by the interface between material science and regenerative engineering and how it can address specific problems related to tissue development, repair, and regeneration. By developing mechanically and strucatally dynamic biomaterials, microfabrication, and matrix manipulation techniques her works aim to recreate complex cell-matrix interactions and model tissue morphogenesis and disease. The ultimate goal of her research is to use these engineered systems to develop and translate more effective therapeutic treatments for diseases such as fibrotic, inflammatory, and congenital disorders. Her lab’s work will initially focus on developing engineering lung alveolar organoids, aiming to build models of acute and chronic pulmonary diseases and for personalized medicine.

Loebel says, “I am grateful to all my Ph.D. and postdoc mentors for their continuous support and especially Jason who, over the last few years, has trained me in becoming an independent scientist and mentor. This transition would not have been possible without such a great mentor team behind me.”

Congratulations Dr. Loebel from everyone at Penn Bioengineering!

Alumni Spotlight: Christopher B. Rodell

Christopher B. Rodell completed his Ph.D. in Penn Bioengineering in 2016 and has since gone on to complete a postdoc at the Center for Systems Biology at Massachusetts General Hospital and Harvard Medical School. He is now an Assistant Professor in the School of Biomedical Engineering, Science and Health Systems at Drexel University. Chris caught up with the BE Blog to talk about his love of Philly and the Penn Bioengineering community:

Chris Rodell, Ph.D.

“Yes, Penn is a great place to study – it’s full of brilliant instructors and classmates. No big surprises there. But Penn Bioengineering is so much more than that! It’s a community with passion, grit, and great times that reflect the city as a whole.

I grew up in the South, so I didn’t really know much about the school or Philly in general when I first visited. But what stood out to me was the people. From the professors to the grad students and even the other visiting students, nearly everyone I met was genuinely excited to talk about their work and just wanted to have a good time doing it. Looking back, I realize that’s exactly what I needed to thrive in a research-based education. Whether studying for a class or pulling long hours at lab, it takes some grit to make it through an engineering degree. But being passionate and having others to share your excitement with make it fun. Penn Bioengineering is a really unique place where I always felt welcome to talk with anyone – the sense of community and openness is probably one of the biggest reasons for their great success in education, research, and productive collaboration.

Through my time at Penn, I was fortunate enough to work with Jason Burdick who is, as everyone told me, ‘one of smartest and nicest people you’ll ever meet.’ I also had the opportunity to build a network of lifelong friends and mentors that span the school of engineering, the medical school, and the broader academic community of Philadelphia. These connections have continued to provide me a sense of community as I embark on an independent research career at Drexel, and I’m excited to be back in Philly!”

This post is part of BE’s Alumni Spotlight series. Read more testimonies from BE Alumni on the BE website.

Alumni Spotlight: Danielle Rossi

Danielle Rossi (M.S.E. 2018)

Danielle Rossi earned her M.S.E. in Bioengineering in December 2018 and is now a R&D Leadership and Development Program Engineer with Johnson & Johnson Medical Devices. Here she reminisces about her research opportunities at Penn and her fond memories of Philly.

“When I first started at Penn, I was amazed by all of the opportunities to learn, to challenge myself, to network, and to innovate. My time at Penn was filled with interesting classes, dedicated faculty, challenging problems to solve, and collaboration. From writing a mock NIH research grant for a tissue engineered Intervertebral Disk in BE 553, to designing an electromechanical device controlled with muscle movement in BE 570, to writing up a business plan and pitching to investors in EAS 546, every new day came with a new venture.

On top of the exciting classes and projects, Penn has numerous research labs and healthcare facilities so that students can apply their skills to real-world problems. While I was a student, I had the opportunity to work at the Abramson Cancer Center in the Cancer Risk Evaluation Program. The program focused on patient risk evaluations, including genetic testing for certain cancers such as breast, ovarian, and sarcoma. This exposed me to the healthcare environment and gave me a new perspective on preemptive medicine.

During my free time, I loved to tour the historically and culturally rich city of Philadelphia. I have the fondest memories of exploring the city with my BE friends and storming the Philly streets when the Eagles won the Super Bowl!

While at Penn, I was sure to utilize Career Services to help me spruce up my resume and interview skills. I was lucky enough to meet with Johnson & Johnson Medical Devices at a Penn career fair and was offered a spot in the R&D Leadership and Development Program. The program allows me to rotate through three different J&J Medical Device companies as an R&D Engineer to gain exposure to new product development, mechanical design, computational modeling, manufacturing, design quality and more. ”

This post is part of BE’s Alumni Spotlight series. Read more testimonies from BE Alumni on the BE website.