Michael Mitchell Receives BMES Rising Star Award

Michael Mitchell, PhD, Skirkanich Assistant Professor of Innovation in the Department of Bioengineering at Penn, has been honored with a Rising Star Award in Cellular and Molecular Bioengineering from the Biomedical Engineering Society (BMES). According to the BMES website, “The BMES Cellular and Molecular Bioengineering Special Interest Group brings together researchers with diverse scientific and clinical interests with a common goal of understanding and engineering molecules, cells, their interactions and microenvironments in the pursuit of controlling biological processes and improving the practice of medicine.” Dr. Mitchell received the award and delivered a lecture at the 2019 Cellular and Molecular Bioengineering Conference in San Diego, California in January, 2019.

One of six early-stage investigators from across the nation to receive the honor, Dr. Mitchell was recognized for his work on engineering delivery technologies for cancer gene therapy and immunotherapy, which is helping to lay the foundation for a new class of therapeutic strategies against hematologic cancers such as multiple myeloma and leukemia. In 2018, Dr. Mitchell was awarded the NIH Director’s New Innovator Award for this research, and received the Burroughs Wellcome Fund Career Award at the Scientific Interface) in 2016. He joined the Penn faculty in January 2018 after completing an NIH NCI postdoctoral fellowship with Dr. Robert Langer at the Koch Institute for Integrative Cancer Research at MIT.

Chairs for BMES ’19 to Include Burdick

chairsJason Burdick, Ph.D., who is a professor in the University of Pennsylvania’s Department of Bioengineering, has been named one of the three chairs of the 2019 annual meeting of the Biomedical Engineering Society (BMES), which be held here in Philadelphia on October 16-19. Dr. Burdick will share this position with two other Philadelphians: Alisa Morss Clyne, Ph.D., an associate professor of mechanical engineering and mechanics at Drexel University; and Ruth Ochia, Ph.D., an associate professor of instruction in bioengineering at Temple University. Drs. Burdick, Clyne, and Ochia will share the responsibility for planning the meeting and chairing it once it is in session.

“I am very happy to be appointed as a program chair for the 2019 BMES meeting in Philadelphia, along with Alisa Morss Clyne of Drexel University and Ruth Ochia of Temple University,” Dr. Burdick said when asked about the honor. “The three of us felt that it was important to represent the various biomedical engineering research and education programs within the city of Philadelphia, since the meeting will be held here.  There is such a wealth of biomedical engineering efforts in Philly that provides great opportunities to engage in outreach and interaction with both the community and local industry during the meeting.”

Sperry Wins BMES Design and Research Award

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Megan Sperry

Megan Sperry, a Ph.D. student in the Department of Bioengineering, is a recipient of a Student Design and Research Award from the Biomedical Engineering Society (BMES). Megan works in the Spine Pain Research Lab of Beth Winkelstein, Ph.D., professor of Bioengineering and Vice Provost for Education at Penn’s School of Engineering and Applied Science, as well as with Eric Granquist, DMD, MD, an oral and maxillofacial surgeon at Penn Dental Medicine.

With Drs. Winkelstein and Granquist, Megan studies temporomandibular joint (TMJ) pain and osteoarthritis, the latter of which can develop as a long-term consequence of untreated TMJ dysfunction.  There’s currently no way to determine which patients will progress to TMJ osteoarthritis, so Megan’s extended abstract, which was submitted to the BMES competition, detailed a study using 18F-EF5 PET, an imaging modality used mainly in oncology. Hypothesizing that hypoxia, or low oxygen, was a key factor in the development of TMJ osteoarthritis, Megan studied the relationship between hypoxia and persistent TMJ pain and found that hypoxia preceded reorganization of the cartilage of the TMJ, part of the process culminating in TMJ osteoarthritis (see image below).

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An example of 18F-EF5-PET imaging of the TMJ.

“This project has been both fun and challenging because it brings together concepts and techniques from multiple fields, including orthopedics, neuroscience, and, with the use of 18F-EF5, radiation oncology,” Megan said. “I’m excited to have the opportunity to share my work at the BMES Annual Meeting and receive feedback as we continue to move the project forward.”

Each year, BMES awards up to five graduate students the Student Design and Research Award from dozens of submissions. Congratulations to Megan for this elite recognition of her research!

BMES at Penn Wins Outreach Award

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The chapter of the Biomedical Engineering Society (BMES) at the University of Pennsylvania has won the Student Outreach Achievement Award from the society. This is the second time in three years that BMES at Penn has won the award, for which more than 60 other chapters compete.

The award acknowledges the efforts of Penn BMES to establish relationships with the surrounding community. For instance, Junior Beta Day, held in the spring semester, saw Penn BE students hosting approximately 60 local middle school students for a day on campus, during which they interacted with members of the faculty and engaged in activities centered on bioengineering. In addition, the Penn BMES chapter has participated in local neighborhood revitalization initiatives and acted as mentors.

“I’m very proud of our group’s outreach initiatives within the both the greater Philadelphia and campus communities,” said Sonia Bansal, who is one of the outreach chairs for the chapter. “Our partnerships with iPraxis and SPARK help us break down bioengineering concepts into approachable activities for middle school students. We hope that our programming shows students that they too can go on to be engineers and scientists, and its an incredibly rewarding experience to see students get excited about STEM.”

Founded in 1968, BMES is a 501(c)(3) nonprofit professional association acting as a lead society for 7,000 members and 115 student chapters.