Daeyeon Lee, Professor and Evan C Thompson Term Chair for Excellence in Teaching in the Department of Chemical and Biomolecular Engineering and member of the Penn Bioengineering Graduate Group, is the recipient of two recent honors.
“Students who feel connected with instructors and among peers will invest more time, work harder, and retain information better, because they feel comfortable and safe being in the classroom and making space,” Lee said in his opening remarks. “So, there are clearly lots of positive benefits to having this connectedness among students in the classroom.”
Lee’s lecture, titled “(Re)connecting in the Classroom,” was inspired by the “Great Disengagement” referenced in an article published in The Chronicle of Higher Education last year. It portrayed students as more disconnected and uncertain as they re-entered the campus environment.
Read more about Lee’s “(Re)connecting in the Classroom” in Penn Today.
In addition, Lee has received the 2022 Outstanding Achievement Award in Nanoscience from the American Chemical Society (ACS).
The annual award recognizes exceptional achievements in nanoscience research and notable leadership in the area of colloidal nanoparticles and application. Lee was chosen from a large group of extraordinary nominees among the invited speakers, “for pioneering research in development of factory-on-a-chip and its application for large scale nanoparticle synthesis and functionalization.”
Two faculty affiliated with the Department of Bioengineering at the University of Pennsylvania have been elected to the American Academy of Arts & Sciences. They join nearly 270 new members honored in 2023, recognized for their excellence, innovation, leadership, and broad array of accomplishments.
Nader Engheta is the H. Nedwill Ramsey Professor, with affiliations in the departments of Electrical and Systems Engineering (primary appointment), Bioengineering (secondary appointment) and Materials Science and Engineering (secondary appointment) in the School of Engineering and Applied Science; and Physics and Astronomy (secondary appointment) in the School of Arts & Sciences. His current research activities span a broad range of areas including optics, photonics, metamaterials, electrodynamics, microwaves, nano-optics, graphene photonics, imaging and sensing inspired by eyes of animal species, microwave and optical antennas, and physics and engineering of fields and waves. He has received numerous awards for his research, including the 2023 Benjamin Franklin Medal in Electrical Engineering, the 2020 Isaac Newton Medal and Prize from the Institute of Physics (U.K.), the 2020 Max Born Award from OPTICA (formerly OSA), induction to the Canadian Academy of Engineering as an International Fellow (2019), U.S. National Academy of Inventors (2015), and the Ellis Island Medal of Honor from the Ellis Island Honors Society (2019). He joins four other Penn faculty elected to the Academy this year.
Read the announcement and the full list of Penn electees in Penn Today.
Susan Margulies, Professor in the Wallace H. Coulter Department of Biomedical Engineering in the College of Engineering at Georgia Tech, was also elected. Margulies is both Professor Emeritus in Penn Bioengineering and an alumna of the program, having earned her Ph.D. with the department in 1987. Margulies is an expert in pediatric traumatic brain injury and lung injury. She previously served as Chair of Biomedical Engineering at Georgia Tech/Emory University and in 2021 became the first biomedical engineer selected to lead the National Science Foundation’s (NSF) Directorate of Engineering.
Read the announcement of Margulies’ elected to the Academy at Georgia Tech.
Researchers at the University of Pennsylvania, AMOLF, and the City University of New York (CUNY) have created a surface with a nanostructure capable of solving mathematical equations.
Powered by light and free of electronics, this discovery introduces exciting new prospects for the future of computing.
Engheta is the founder of the influential field of “optical metatronics.” He creates materials that interact with photons to manipulate data at the speed of light. Engheta’s contribution to this study marks an important advance in his quest to use light-matter interactions to surpass the speed and energy limitations of digital electronics, bringing analog computing out of the past and into the future.
“I began the work on optical metatronics in 2005,” says Engheta, “wondering if it were possible to recreate the elements of a standard electronic circuit at nanoscale. At this tiny size, it would be possible to manipulate the circuit with light, rather than electricity. After achieving this, we became more ambitious, envisioning collections of these nanocircuits as processors. In 2014, we were designing materials that used these optical nanostructures to perform mathematical operations, and in 2019, we anted up to entire mathematical equations using microwaves. Now, my collaborators and I have created a surface that can solve equations using light waves, a significant step closer to our larger goals for computing materials.”
The study, recently published in Nature Nanotechnology, demonstrates the possibility of solving complex mathematical problems and a generic matrix inversion at speeds far beyond those of typical digital computing methods.
The solution converges in about 349 femtoseconds (less than one trillionth of a second), orders of magnitude faster than the clock speed of a conventional processor.
Nader Engheta is the H. Nedwill Ramsey Professor in the Departments of Electrical and Systems Engineering and in Bioengineering in the School of Engineering and Applied Science and Professor in Physics and Astronomy in the School of Arts & Sciences at the University of Pennsylvania.
The American Association for Cancer Research (AACR), the largest cancer research organization in the country and based in Philadelphia, will bestow its 2023 Award for Lifetime Achievement in Cancer Research to Carl June, Richard W. Vague Professor in Immunotherapy in the Department of Pathology and Laboratory Medicine at Penn Medicine. June is also Director of the Center for Cellular Immunotherapies, Director of the Parker Institute for Cancer Immunotherapy, and member of the Penn Bioengineering Graduate Group. He is recognized for his groundbreaking work in developing the first gene-editing cell therapy for cancer and for his pioneering work with CAR T cell therapy.
LeAnn Dourte, Practice Associate Professor in Bioengineering, has been awarded a 2023 Provost’s Award for Teaching Excellence by Non-Standing Faculty.
“This award reflects LeAnn’s innovation and dedication in teaching our students in Bioengineering’s biomechanics, biomaterials and biomechatronics classes and labs,” says Ravi Radhakrishnan, Professor and Chair of Bioengineering. “She is a core member of our teaching faculty, spearheading the Department’s initiatives to improve experiential learning and classroom experiences through the SAIL model of education.”
The Structured, Active, In-Class Learning (or SAIL) model of education emphasizes teamwork and dynamic problem-solving. According to Penn’s Center for Teaching and Learning (CTL), SAIL “provides students with the opportunity to struggle through the application of course ideas and material, often the most difficult part of learning for students, with guidance from instructors as well as help from their peers.”
In addition to her pedagogical interests, Dourte serves on the Bioengineering Climate Committee and is also highly involved in student wellness programming, serving as the Department’s Wellness Ambassador for the School.
The Provost’s Awards for Teaching Excellence by Non-Standing Faculty were established in 1988.
There was a time before time when the universe was tiny, dense, and hot. In this world, time didn’t even exist. Space didn’t exist. That’s what current theories about the Big Bang posit, says Vijay Balasubramanian, the Cathy and Marc Lasry Professor of Physics. But what does this mean? What did the beginning of the universe look like? “I don’t know, maybe there was a timeless, spaceless soup,” Balasubramanian says. When we try to describe the beginning of everything, “our words fail us,” he says.
Yet, for thousands of years, humans have been trying to do just that. One attempt came 75 years ago from physicists George Gamow and Ralph Alpher. In a paper published on April 1, 1948, Alpher and Gamow imagined the universe starts in a hot, dense state that cools as it expands. After some time, they argued, there should have been a gas of neutrons, protons, electrons, and neutrinos reacting with each other and congealing into atomic nuclei as the universe aged and cooled. As the universe changed, so did the rates of decay and the ratios of protons to neutrons. Alpher and Gamow were able to mathematically calculate how this process might have occurred.
Now known as the alpha-beta-gamma theory, the paper predicted the surprisingly large fraction of helium and hydrogen in the universe. (By weight, hydrogen comprises 74% of nuclear matter, helium 24%, and heavier elements less than 1%.)
The findings of Gamow and Alpher hold up today, Balasubramanian says, part of an increasingly complex picture of matter, time and space. Penn Today spoke with Balasubramanian about the paper, the Big Bang, and the origin of the universe.
Balasubramanian is Cathy and Marc Lasry Professor in the Department of Physics and Astronomy in the Penn School of Arts and Sciences and a member of the Penn Bioengineering Graduate Group.
When Brian Litt of the Perelman School of Medicine and School of Engineering and Applied Science began treating patients as a neurologist, he found that the therapies and treatments for epilepsy were mostly reliant on traditional pharmacological interventions, which had limited success in changing the course of the disease.
People with epilepsy are often prescribed anti-seizure medications, and, while they are effective for many, about 30% of patients still continue to experience seizures. Litt sought new ways to offer patients better treatment options by investigating a class of devices that electronically stimulate cells in the brain to modulate activity known as neurostimulation devices.
Litt’s research on implantable neurostimulation devices has led to significant breakthroughs in the technology and has broadened scientists’ understanding of the brain. This work started not long after he came to Penn in 2002 with licensing algorithms to help drive a groundbreaking device by NeuroPace, the first closed-loop, responsive neurostimulator to treat epilepsy.
Building on this work, Litt noted in 2011 how the implantable neurostimulation devices being used at the time had rigid wires that didn’t conform to the brain’s surface, and he received support from CURE Epilepsy to accelerate the development of newer, flexible wires to monitor and stimulate the brain.
“CURE is one of the epilepsy community’s most influential funding organizations,” Litt says. “Their support for my lab has been incredibly helpful in enabling the cutting-edge research that we hope will change epilepsy care for our patients.”
Penn Engineering announced the faculty recipients of the 2023 Student Choice Awards (formerly the Teaching and Advising Awards). Each year, the Penn Engineering undergraduate student body thoughtfully selects the recipients of these awards for their dedication in teaching, mentorship and student advocacy. This year also features two new awards, the Student Advocacy Award and the Undergraduate Research Mentoring Award.
Brit Shields, Senior Lecturer in Bioengineering, is the inaugural recipient of the Student Advocacy Award. This award is presented to a member of the Penn Engineering faculty by the Underrepresented Student Advisory Board in Engineering in recognition of their outstanding commitment to women and underrepresented student advocacy, equity and inclusion.
Shields completed a Ph.D. at Penn in 2015 in History and Sociology of Science, with a dissertation on scientific diplomacy through the example of Richard Courant and New York University, where Shields completed an M.A. in Humanities and Social Thought: Science Studies.
She was promoted to Senior Lecturer in Bioengineering in 2019. She has brought her expertise in the history and sociology of science to her leading role in developing and improving the ethics curriculum for all students in the School of Engineering and Applied Science.
Read other stories featuring Brit Shields in the BE Blog.
Read the full list of 2023 Penn Engineering Student Choice Award Winners in Penn Engineering Today.
His research aims to combat global health threats such as COVID-19 and Alzheimer’s disease by better understanding how proteins function and malfunction, especially through new computational and experimental methods that map protein structures. This understanding of protein dynamics can lead to effective new treatments for even the most seemingly resistant diseases.
“Delivering the right treatment to the right person at the right time is vital to sustaining—and saving—lives,” Magill said. “Greg Bowman’s novel work holds enormous promise and potential to advance new forms of personalized medicine, an area of considerable strength for Penn. A gifted researcher and consummate collaborator, we are delighted to count him among our distinguished PIK University Professors.”
Bowman came to Penn from the Washington University School of Medicine’s Department of Biochemistry and Molecular Biophysics, where he served on the faculty since 2014. He previously completed a three-year postdoctoral fellowship at the University of California, Berkeley.
Bowman’s research utilizes high-performance supercomputers for simulations that can better explain how mutations and disease change a protein’s functions. These simulations are enabled in part through the innovative Folding@home project, which Bowman directs. Folding@home empowers anyone with a computer to run simulations alongside a consortium of universities, with more than 200,000 participants worldwide.
His research has been supported by the National Science Foundation, National Institutes of Health, National Institute on Aging, and Packard Foundation, among others, and he has received a CAREER Award from the NSF, Career Award at the Scientific Interface from the Burroughs Wellcome Fund, and Thomas Kuhn Paradigm Shift Award from the American Chemical Society. He received a Ph.D. in biophysics from Stanford University and a B.S. (summa cum laude) in computer science, with a minor in biomedical engineering, from Cornell University.
“Greg Bowman’s highly innovative work,” Winkelstein said, “exemplifies the power of our interdisciplinary mission at Penn. He brings together supercomputers, biophysics, and biochemistry to make a vital impact on public health. This brilliant fusion of methods—in the service of improving people’s lives around the world—will be a tremendous model for the research of our faculty, students, and postdocs in the years ahead.”
The Penn Integrates Knowledge program is a University-wide initiative to recruit exceptional faculty members whose research and teaching exemplify the integration of knowledge across disciplines and who are appointed in at least two schools at Penn.
The Louis Heyman University Professorship is a gift of Stephen J. Heyman, a 1959 graduate of the Wharton School, and his wife, Barbara Heyman, in honor of Stephen Heyman’s uncle. Stephen Heyman is a University Emeritus Trustee and member of the School of Nursing Board of Advisors. He is Managing Partner at Nadel and Gussman LLC in Tulsa, Oklahoma.
Election to the AIMBE College of Fellows is among the highest professional distinctions accorded to a medical and biological engineer, with AIMBE Fellows representing the top 2% of medical and biological engineers. College membership honors those who have made outstanding contributions to “engineering and medicine research, practice, or education” and to “the pioneering of new and developing fields of technology, making major advancements in traditional fields of medical and biological engineering, or developing/implementing innovative approaches to bioengineering education.”
Nominated and reviewed by peers and members of the College of Fellows, de la Fuente was elected Fellow “for the development of novel antimicrobial peptides designed using principles from computation, engineering and biology.”
A formal ceremony will be held during the AIMBE Annual Event in Arlington, Virginia on March 27, 2023, where de la Fuente will be inducted along with 140 colleagues who make up the AIMBE College of Fellows Class of 2023.
AIMBE Fellows are among the most distinguished medical and biological engineers, including 3 Nobel Prize laureates and 17 Fellows having received the Presidential Medal of Science and/or Technology and Innovation, along with 205 having been inducted into the National Academy of Engineering, 105 into the National Academy of Medicine and 43 into the National Academy of
Sciences.